| 1865 |
First administration of Regents Exams as high school entrance exams |
| 1878 |
First administration of Regents Exams as high school end-of-course exams |
| 1966 |
First administration of the Grades 3, 6, and 9 Pupil Evaluation Program (PEP) Tests in Reading and Mathematics |
| 1979 |
First administration of Regents Competency Tests (RCT) |
| 1983 |
First administration of the Pupil Evaluation Program (PEP) Test in Grade 5 Writing |
| 1984 |
First administration of the Regents Competency Tests |
| 1987 |
First administration of the Program Evaluation Test (PET) in Grade 6 Social Studies |
| 1989 |
First administration of the Program Evaluation Tests (PET) in Grade 4 Science and Grade 8 Social Studies |
| 1999 |
First administration of the Grade 4 and Grade 8 Tests in ELA and Math |
| 1999-2004 |
First administrations of Elementary- and Intermediate-level Science Tests and Regents Exams in English Language Arts, Math, and Science aligned to 1996 Learning Standards and Regents Exams in Social Studies aligned to 1998 Core Curriculum |
| 2000 |
First administration of the New York State Alternate Assessment (NYSAA) |
| 2001 |
First administration of the Grade 8 Intermediate-Level Science Test and the Grade 5 and Grade 8 Social Studies Tests |
| 2003 |
First administration of the New York State English as a Second Language Achievement Test (NYSESLAT) |
| 2004 |
First administration of the Grade 4 Elementary-Level Science Test |
| 2006 |
First administration of the Grades 3–8 Tests in ELA and Math |
| 2008-2010 |
First administration of Regents Exams in Math aligned to 2005 Mathematics Learning Standards |
| 2013 |
First administration of the Grades 3–8 Tests in ELA and Math aligned to Common Core Learning Standards |
| 2014-16 |
First administrations of Regents Exams in ELA and Math aligned to Common Core Learning Standards |
| 2019 |
First administration of Regents Exam in Global History and Geography II aligned to NYS K-12 Social Studies Framework |